Health feed - News BreaK Tuesday, April 4, 2023 6:53 PM The CDC and Dr. Anthony Fauci keep pushing hard for all healthy children to have four doses of the COVID vaccine despite the lack of clinical-outcomes data to support the... |
Health feed - News BreaK Tuesday, April 4, 2023 6:49 PM U.S. Surgeon General Dr. Vivek Murthy met with Pittsburghers to hear firsthand about things happening in our area to improve our mental health. |
Health feed - News BreaK Tuesday, April 4, 2023 6:21 PM Conservative commentator and strategist Bill Kristol talks about the meaning of conservatism today, the state of the Republican Party, the health of American democracy and more. |
Health feed - News BreaK Tuesday, April 4, 2023 6:17 PM When the COVID-19 pandemic first hit, most hospitals around the country had to pause annual checkups and medical screenings, and they're still catching up. |
Health feed - News BreaK Tuesday, April 4, 2023 5:55 PM PHILADELPHIA - A Philadelphia man has been sentenced to five years in federal prison for his role in a police car being set on fire outside Philadelphia's City Hall during 2020... |
Health feed - News BreaK Tuesday, April 4, 2023 4:39 PM By MATTHEW PERRONE WASHINGTON - The manufacturer of eyedrops recently linked to deaths and injuries lacked measures to assure sterility at its factory in India, according to... |
Health feed - News BreaK Tuesday, April 4, 2023 4:35 PM The South Florida Sun Sentinel's Chris Perkins and David Furones discuss health concerns for Dolphins quarterback Tua Tagovailoa, offensive tackle Terron Armstead and other key... |
Health feed - News BreaK Tuesday, April 4, 2023 4:33 PM On this special episode, we're talking all about voice! Neda Lahidji is an actor, singer, vocal health coach, voice teacher and a certified vocal health first aider. She... |
Health feed - News BreaK Tuesday, April 4, 2023 4:01 PM The review found that the methodology of many previous studies was flawed and that risk of myriad health problems increased significantly after less than two drinks a day for... |
Health feed - News BreaK Tuesday, April 4, 2023 3:45 PM Johnny Louis/Getty Images CVS has nearly 10,000 pharmacies and dispenses nearly 27% of total retail prescriptions in the US. The pharmacy's customer-loyalty percentage is... |
WebMD Health Tuesday, April 4, 2023 2:24 PM Persistent fatigue — the feeling of having no energy — can contribute to frailty and affects 40% to 74% of older patients with chronic illness. Yet its causes can be elusive. |
WebMD Health Tuesday, April 4, 2023 2:18 PM Emerging research has identified a checklist of sorts that doctors should consider when a patient seeks care for what appears to be long COVID. Here's what to know. |
WebMD Health Tuesday, April 4, 2023 2:14 PM The full health risks of wearing apparel made with PFAS, also known as "forever chemicals," are still unknown. But states are taking action so clothing makers will remove them. |
WebMD Health Tuesday, April 4, 2023 1:12 PM For women with "focal breast complaints" -- issues with pain, lumps or discharge -- ultrasound is an effective diagnostic tool, according to new research. |
WebMD Health Tuesday, April 4, 2023 1:06 PM Carbon monoxide (CO) from generators used to temporarily restore power can be dangerous and can kill in minutes. |
Mark's Daily Apple Tuesday, April 4, 2023 12:00 PM Biological systems are self-maintaining. They have to be. Your cells are little factories, performing tasks crucial to maintaining this thing we call life. And just like in factories, machinery (organelles) break down. Waste (metabolic byproducts) must be managed. Security teams need to be in place to keep intruders (bacteria and viruses) from disrupting operations. For life to sustain itself, cells must perform this crucial work themselves. It's not like we can send in microscopic maintenance workers, mechanics, and security details to handle the dirty work from the outside. Not really, not yet anyway. One of the most important types of biological maintenance is a process called autophagy. Not that long ago, nobody except the most hard-core biohackers talked about autophagy. It has become a hot topic, though, as scientists have made considerable progress toward understanding the ins and outs of autophagy in the past few decades. Now, anyone with a passing interest in longevity or intermittent fasting tosses the word around in casual conversation. But for all the popular interest in autophagy, I'm willing to bet that the average person doesn't understand it all that well. They probably believe that autophagy is desirable, and they may know that intermittent fasting will net them more of it, but that's about it. So today I'm going to answer some autophagy FAQs—what it is, how to induce it, and where you may need to be cautious. What Is Autophagy? Autophagy: the word comes from the Greek for "self-eating," and that's a very accurate description. There are several different types of autophagy. The one that we generally mean when we say "autophagy" involves organelles within the cell called lysosomes "eating"—or rather, using enzymes to degrade—parts of the cell that are damaged or malfunctioning. The overarching goal of autophagy is to maintain homeostasis within the cell—to keep the factory running smoothly. It's a type of cellular recycling process, allowing organelles, proteins, and other structures to be broken down and reused by the cell for energy or building new components. Lysosomes can also degrade pathogens that threaten the integrity of the cell. What Activates Autophagy in the Cells? Autophagy is operating all the time to manage the basic cellular housekeeping, but anything that threatens homeostasis in the cell will ramp it up. Oxygen deprivation (hypoxia), DNA damage, infection, or cellular damage due to factors like oxidative stress can all trigger a rise in autophagy. The trigger we talk about most is nutrient deprivation. Your cells are exquisitely tuned in to how much energy is available. They have multiple systems in place to sense if energy supplies are adequate and to flag when they are low. When energy is abundant, autophagy operates in the background; but when your cells sense that energy is low, they go into conservation mode, and autophagy really kicks in. You can understand why this would be. In lean times, your cells must be more frugal, using what they already have on hand. Breaking down damaged proteins and organelles for firewood and parts to build … Continue reading "What Is Autophagy?" The post What Is Autophagy? appeared first on Mark's Daily Apple. |
