Coronavirus vaccine | Blocking tau spread | Sex differences in autism

Microneedle coronavirus vaccine triggers immune response in mice; blocking receptor stops spread; gene linked to autism sex differences

April 14, 2020 Edition

COVID-19 is an emerging, rapidly evolving situation, and we at NIH are doing everything we can toward the development of diagnostics, therapeutics, and vaccines. You can find the latest public health information from CDC at www.coronavirus.gov and the latest research information from NIH at www.nih.gov/coronavirus. Meanwhile, science continues to progress on many other fronts, and we will continue to try to bring you stories across a wide range of topics.

Researcher holding microneedle array on fingertip

Microneedle coronavirus vaccine triggers immune response in mice

When delivered to mice using microneedles, an experimental vaccine for COVID-19 caused antibody production against the disease within two weeks.


Neuron with tau tangles

Blocking cellular receptor stops spread of tau in mouse brains

In experiments in cells and mice, blocking a cell receptor called LPR1 stopped both normal and harmful forms of tau, which are involved in dementias, from spreading between neurons.


Neuron

Gene linked to sex differences in autism

Researchers found that a small cluster of mutations in the NLGN4X gene, which has been linked to autism spectrum disorder, may explain the sex differences tied to the gene.


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